NIST Compliance

NIST Compliance

NIST compliance refers to adherence to the standards and guidelines established by the National Institute of Standards and Technology (NIST). A non-regulatory agency of the United States Department of Commerce. NIST develops and publishes standards, best practices, and recommendations to help organizations ensure the security, privacy, and integrity of their information systems and data. It was created via an executive order from President Obama in 2013 to improve cybersecurity within critical infrastructure.

One of the most well-known NIST publications is the NIST Special Publication 800-53, “Security and Privacy Controls for Federal Information Systems and Organizations.” This document provides a comprehensive set of security controls that organizations can implement to protect their information systems.

NIST Compliance

NIST compliance is often associated with government agencies and contractors that handle sensitive information. But it is also widely adopted by private sector organizations. Compliance with NIST standards is seen as a best practice for enhancing cybersecurity posture and managing risks effectively.

To ensure NIST compliance and enhance your organization’s cybersecurity posture, it is crucial to adopt various practices, policies, and tools. Sepio offers an effective solution that aligns with NIST cybersecurity framework (NIST CSF Compliance). Provides a risk-based approach to identify, assess, and prioritize cybersecurity risk management.

Key Areas Covered by NIST Compliance:

Risk Management Framework: NIST provides a structured approach for managing information security risk through a continuous process of selecting, implementing, monitoring, and assessing security controls.

Security Controls: NIST outlines a set of security controls that organizations can implement to safeguard their information systems. These controls cover areas such as access control, encryption, incident response, and system monitoring.

Security and Privacy Frameworks: NIST provides frameworks and guidelines for both security and privacy. Including the Cybersecurity Framework (CSF) and the Privacy Framework. These frameworks help organizations manage and improve their cybersecurity and privacy programs.

Authentication and Identity Management: NIST standards provide guidance on authentication practices and identity management to ensure that only authorized individuals have access to sensitive systems and data.

Physical Layer Visibility and NIST Compliance

Traditional cybersecurity solutions often overlook physical layer (OSI model), also known as the physical layer visibility. Resulting in incomplete asset inventories, unidentified vulnerabilities, and ignored risks. These limitations hinder overall cybersecurity efforts and prevent full alignment with the NIST cybersecurity framework. Consequently, enterprises face weaker cybersecurity and resilience capabilities, exposing them to significant risks.

However, for organizations to meet NIST cybersecurity framework compliance, they must adopt a comprehensive approach toward cyber security. Ranging from various practices, policies, and tools.

How Sepio Helps with NIST Compliance

FunctionPurposeSepio NIST Cybersecurity Framework Compliance


Develop the organizational understanding to manage cybersecurity risk to systems, assets, data, and capabilities.Sepio’s Asset Risk Management (ARM) platform detects and identifies all known and shadow IT, OT and IoT assets on a network, at any scale. By harnessing properties at the physical layer, Sepio generates an objective DNA profile and contextual Asset Risk Factor (ARF) score for every connected asset, regardless of its functionality and operability. The unique approach and patented algorithm mean Sepio is untainted by misleading profile perceptions or behavioral assumptions that deceive even the most robust cyber tools. With Sepio’s actionable visibility, enterprise security teams instantly know what needs attention and better understand their asset risk surface.


Develop and implement appropriate safeguards to ensure the delivery of critical services.The Sepio platform controls asset risk by automatically enforcing specific hardware usage through predefined granular access controls, fortifying zero trust initiatives. This prevents unwanted and uncontrolled assets from gaining access to critical infrastructure. Sepio maintains asset visibility and verification through continuous monitoring to provide constant protection at any scale.


Develop and implement appropriate activities to identify the occurrence of a cybersecurity event.Sepio detects behavioral changes and anomalies that could indicate a significant cybersecurity threat. The platform’s internal database provides up to date threat intelligence on known-to-be-vulnerable assets, further optimizing efficiency by allowing Sepio to discover emerging threats (data quality).


Develop and implement appropriate activities to take action regarding a detected cybersecurity incident.Sepio alerts enterprises of high-medium-low risks to expedite time to resolution and prevent crises. When an asset breaches a pre-set rule or gets recognized as a known attack tool (hardware attack), Sepio instantly sends an alert and initiates a pre-emptive and automated mitigation process that blocks the device through third-party tools.  


Develop and implement appropriate activities to maintain resilience plans and restore any capabilities or services that were impaired due to a cybersecurity incident.The Sepio platform logs and documents all events that occur on the network, thus providing information that can be utilized in post-event analysis to help improve and strengthen cybersecurity efforts.

NIST Compliance with Sepio’s Asset Risk Management

Sepio’s innovative solution provides layer 1 visibility. Enabling organizations to meet a wide range of cybersecurity framework controls (CSF), from the initial identification to effective response. By leveraging Layer 1 data, Sepio accurately detects and identifies all IT/OT/IoT assets connected through USB and network interfaces. This includes managed, unmanaged, and hidden assets. Empowering you to gain a comprehensive understanding of your infrastructure and effectively address potential vulnerabilities.

Sepio’s Asset Risk Management solution streamlines NIST compliance for your organization. By leveraging the framework’s five core functions (Identify, Protect, Detect, Respond, and Recover) and aligning with other NIST standards and best practices, Sepio offers a flexible and repeatable approach to managing cybersecurity risks. This comprehensive solution empowers you to safeguard critical infrastructure, optimize resource allocation, and mitigate potential threats cost-effectively.

Secure Your Organization with Sepio’s NIST Compliance Solution

In conclusion, achieving NIST compliance is paramount in today’s cybersecurity landscape. By embracing Sepio’s Asset Risk Management solution, you can ensure NIST compliance. Strengthen your cybersecurity posture, and confidently protect your organization’s sensitive information and critical assets. Take advantage of Sepio’s layer 1 visibility to manage risks effectively and enhance your overall cybersecurity resilience.
Sepio’s solution offers Layer 1 visibility to help enterprises fulfill many of the CSF controls, from Identify to Respond. By using Layer 1 data to accurately detect and identify all IT/OT/IoT assets on USB and network interfaces – managed, unmanaged, and hidden.

See every known and shadow asset. Prioritize and mitigate risks.
Talk to an expert. Our experts will help you understand how to use Sepio’s patented technology to gain control of your asset risks.

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January 9th, 2023